By MaleProstateHealth • September 28, 2014 • Comments Off on Antimuscarinics For Treatment Of Overactive Bladder
Every year, millions of men are being diagnosed with a condition called BPH or benign prostatic hypertrophy. This condition refers to the excessive growth as well as the increase of cells of the prostate. There has been no exact explanation as to how or why this problem occurs; however, experts believe that men who have familial histories of this problem as well as people who experience hormonal imbalances are more at risk in developing BPH. Some of the most common treatments used for BPH include medications like antimuscarinics for treatment of overactive bladder, alpha blockers, some lifestyle changes, and surgical procedures.
Men who suffer from this condition tend to have their prostates grow into a size which is two to four times larger than normal. Because the prostate gland is situated near the bladder and urethra, its growth later on becomes an obstruction to the urinary flow of men. Some of the most common symptoms of BPH include discomfort during urination, bladder distention, dribbling of urine, and difficulty in urinating. Men who develop BPH are at higher risks of developing sexual conditions, kidney dysfunctions and other prostate problems which will eventually lead to the degradation of the quality of men’s lives. This means that it is necessary for all men to act immediately whenever they experience any of these symptoms.
Antimuscarinics for treatment of overactive bladder are thought to act primarily through antagonism at muscarinic M3 receptors located at neuromuscular junctions in the human bladder detrusor muscle. Several of these drugs have been shown to be efficacious in ameliorating the symptoms of OAB in older patients, but most currently available agents lack selectivity for the M3 receptor subtype, and interaction with other muscarinic receptor subtypes throughout the body may adversely affect a variety of physiological functions and result in unwanted side effects, including cognitive dysfunction.
Although these disadvantages rarely occur, men should still remember that it could still happen. Men who are planning to take antimuscarinics for treatment of overactive bladder should speak about it with their doctors first. This will allow them to understand the benefits as well as the risks there are with this procedure.
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